Natural Hair Growth Supplement for Healthier Hair
TOPK11 has been developed from ingredients proven in randomized controlled trials, which represent the highest standard of reliability in the academic field.


Advanced Hair Growth Supplement for Hair Transplant Patients
Biotechnology focused on addressing the causes of chronic and progressive hair loss. Specially designed for leading hair restoration surgeons in Thailand.

Natural Ingredients
TOPK11 dietary supplement is made from ingredients that have stood the test of time, sourced from food origins, making it safe and harmless.
Designed to FDA Standards
TOPK11 dietary supplement was developed from scratch to meet FDA standards, while still keeping dosing and mechanistic targets as the central focus to drive patient results.
Certified by GMP and ISO
Made in a professional facility with ISO and GMP certifications to ensure consistent quality.
Developed to meet clinical study evidence
TOPK11 dietary supplement has quantities that meet standards and are based on studies, which truly make a difference.
GMP (Good Manufacturing Practices) Certified:

Working Mechanism

Reduce Shedding
TOPK11 actively blocks DHT and TGF-Beta production, halting follicle miniaturization and minimizing premature hair fall without causing any harmful hormonal side effects.

Stimulate Regrowth
By improving blood circulation and deeply nourishing the scalp, it directly revitalizes dormant follicles, encouraging the rapid emergence of new, healthy, and denser hair.

Extend Growth Phase
Potent ingredients like Procyanidin B2 target oxidative stress and mitochondrial function, prolonging the active anagen phase to ensure stronger, longer, and more resilient hair.
Product features
Superior to Conventional Hair Loss Solutions
TOPK11 addresses root causes such as DHT, inflammation, metabolic health, and oxidative stress with natural, science-backed ingredients—far surpassing other non-drug options without added side effects.
Quality & Research
Engineered for excellence
The proof is in the numbers
+14%
Increased hair Density
Published Clinical trials show measurable gains in density. Users report fuller, stronger strands over time.
8 months
Visible results
Backed by RCTs with significant improvements. Noticeable changes in hair health and volume.
4+ years
Of research and development
Grounded in peer-reviewed science and innovation. Developed by globally leading experts focusing on hair loss
Ingredients & Tech
Breakthrough Mechanisms
Not found anywhere else
Unique science-backed pathways targeting hair loss at the cellular and hormonal level.
Signalling Protein Control

Mitochondrial Protection

Innovation
TOPK11 - Developed by top 2% published scientists
Recognized by Stanford University as a top 2% published scientist in medicinal and biomolecular chemistry (2023 and 2024), Systems Trichology co-founder, Dr. Nicholas J. Sadgrove, is a pioneer in hair loss research and nutraceutical innovation.
An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing ‘the Big Eight Strikes’.
The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’.
The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance.
Honest nutraceuticals, cosmetics, therapies, and foods (NCTFs): Standardization and safety of natural products.
The Proof
Before & Afters
Before-and-after photos from a published randomized trial of 250 patients using apple extract showing visible improvement in hair density.

Patient 3

Patient 4

Patient 2

Patient 1
Tenore, G.C et al., 2018. Annurca apple nutraceutical formulation enhances keratin expression in a human model of skin and promotes hair growth and tropism in a randomized clinical trial. Journal of medicinal food, 21(1), pp.90-103.













